A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases

Multiple neurodegenerative diseases are characterized by aggregation of tau molecules. Adult humans express six isoforms of tau that contain either 3 or 4 microtubule binding repeats (3R or 4R tau). Different diseases involve preferential aggregation of 3R (e.g Pick disease), 4R (e.g. progressive su...

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Dades bibliogràfiques
Publicat a:Acta Neuropathol Commun
Autors principals: Metrick, Michael A., Ferreira, Natália do Carmo, Saijo, Eri, Kraus, Allison, Newell, Kathy, Zanusso, Gianluigi, Vendruscolo, Michele, Ghetti, Bernardino, Caughey, Byron
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Methodology Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036215/
https://ncbi.nlm.nih.gov/pubmed/32087764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-020-0887-z
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