Identification and clinical impact of potentially actionable somatic oncogenic mutations in solid tumor samples

BACKGROUND: An increasing number of anti-cancer therapeutic agents target specific mutant proteins that are expressed by many different tumor types. Successful use of these therapies is dependent on the presence or absence of somatic mutations within the patient’s tumor that can confer clinical effi...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:J Transl Med
المؤلفون الرئيسيون: Toomey, Sinead, Carr, Aoife, Mezynski, Mateusz Janusz, Elamin, Yasir, Rafee, Shereen, Cremona, Mattia, Morgan, Clare, Madden, Stephen, Abdul-Jalil, Khairun I., Gately, Kathy, Farrelly, Angela, Kay, Elaine W., Kennedy, Susan, O’Byrne, Kenneth, Grogan, Liam, Breathnach, Oscar, Morris, Patrick G., Eustace, Alexander J., Fay, Joanna, Cummins, Robert, O’Grady, Anthony, Kalachand, Roshni, O’Donovan, Norma, Kelleher, Fergal, O’Reilly, Aine, Doherty, Mark, Crown, John, Hennessy, Bryan T.
التنسيق: Artigo
اللغة:Inglês
منشور في: BioMed Central 2020
الموضوعات:
Research
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036178/
https://ncbi.nlm.nih.gov/pubmed/32087721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02273-4
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