HORMA domain proteins and a Trip13-like ATPase regulate bacterial cGAS-like enzymes to mediate bacteriophage immunity

Bacteria are continually challenged by foreign invaders including bacteriophages, and have evolved a variety of defenses against these invaders. Here, we describe the structural and biochemical mechanisms of a bacteriophage immunity pathway found in a broad array of bacteria, including E. coli and P...

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Vydáno v:Mol Cell
Hlavní autoři: Ye, Qiaozhen, Lau, Rebecca K., Mathews, Ian T., Birkholz, Erica A., Watrous, Jeramie D., Azimi, Camillia S., Pogliano, Joe, Jain, Mohit, Corbett, Kevin D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7036143/
https://ncbi.nlm.nih.gov/pubmed/31932165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.12.009
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