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TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching
The AAA+ family ATPase TRIP13 is a key regulator of meiotic recombination and the spindle assembly checkpoint, acting on signaling proteins of the conserved HORMA domain family. Here we present the structure of the Caenorhabditis elegans TRIP13 ortholog PCH-2, revealing a new family of AAA+ ATPase p...
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| Publicat a: | eLife |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
eLife Sciences Publications, Ltd
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4439613/ https://ncbi.nlm.nih.gov/pubmed/25918846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.07367 |
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