The AAA+ ATPase TRIP13 remodels HORMA domains through N‐terminal engagement and unfolding

Proteins of the conserved HORMA domain family, including the spindle assembly checkpoint protein MAD2 and the meiotic HORMADs, assemble into signaling complexes by binding short peptides termed “closure motifs”. The AAA+ ATPase TRIP13 regulates both MAD2 and meiotic HORMADs by disassembling these HO...

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Publicat a:EMBO J
Autors principals: Ye, Qiaozhen, Kim, Dong Hyun, Dereli, Ihsan, Rosenberg, Scott C, Hagemann, Goetz, Herzog, Franz, Tóth, Attila, Cleveland, Don W, Corbett, Kevin D
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556265/
https://ncbi.nlm.nih.gov/pubmed/28659378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201797291
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