Immuno-genomic landscape of osteosarcoma

Limited clinical activity has been seen in osteosarcoma (OS) patients treated with immune checkpoint inhibitors (ICI). To gain insights into the immunogenic potential of these tumors, we conducted whole genome, RNA, and T-cell receptor sequencing, immunohistochemistry and reverse phase protein array...

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Publicat a:Nat Commun
Autors principals: Wu, Chia-Chin, Beird, Hannah C., Andrew Livingston, J., Advani, Shailesh, Mitra, Akash, Cao, Shaolong, Reuben, Alexandre, Ingram, Davis, Wang, Wei-Lien, Ju, Zhenlin, Hong Leung, Cheuk, Lin, Heather, Zheng, Youyun, Roszik, Jason, Wang, Wenyi, Patel, Shreyaskumar, Benjamin, Robert S., Somaiah, Neeta, Conley, Anthony P., Mills, Gordon B., Hwu, Patrick, Gorlick, Richard, Lazar, Alexander, Daw, Najat C., Lewis, Valerae, Futreal, P. Andrew
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035358/
https://ncbi.nlm.nih.gov/pubmed/32081846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14646-w
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