Analysis of HSP27 and the autophagy marker LC3B+ puncta following preoperative chemotherapy identifies high-risk osteosarcoma patients

Chemotherapy-induced autophagy is a proposed mechanism of chemoresistance and potential therapeutic target in osteosarcoma. We evaluated heat shock protein 27 (HSP27) and autophagy-related proteins as predictors of pathologic treatment response and prognostic markers among osteosarcoma patients who...

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Dettagli Bibliografici
Pubblicato in:Mol Cancer Ther
Autori principali: Livingston, J. Andrew, Wang, Wei-Lien, Tsai, Jen-Wei, Lazar, Alexander J., Leung, Cheuk Hong, Lin, Heather, Advani, Shailesh, Daw, Najat, Santiago-O’Farrill, Janice, Hollomon, Mario, Gordon, Nancy B., Kleinerman, Eugenie S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984702/
https://ncbi.nlm.nih.gov/pubmed/29592877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-0901
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