MAGE-A3 is a Clinically Relevant Target in Undifferentiated Pleomorphic Sarcoma/Myxofibrosarcoma

Melanoma-associated antigen 3 (MAGE-A3) expression is generally restricted to the placenta and germline cells of the testis, but it may also be expressed in sarcoma and other cancers and is associated with poor prognosis. Immunotherapy approaches targeting MAGE-A3 in other cancers have shown mixed r...

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Detalhes bibliográficos
Main Authors: Anthony P. Conley, Wei-Lien Wang, John A. Livingston, Vinod Ravi, Jen-Wei Tsai, Ali Ali, Davis R. Ingram, Caitlin D. Lowery, Christina L. Roland, Neeta Somaiah, Patrick Hwu, Cassian Yee, Vivek Subbiah, Andrew Futreal, Alexander J. Lazar, Shreyaskumar Patel, Jason Roszik
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-05-01
Colecção:Cancers
Assuntos:
MAGEA3
MAGE family member A3
cancer testis antigen
immunotherapy
adoptive T cell therapy
sarcoma
pleomorphic sarcoma
undifferentiated pleomorphic sarcoma
myxofibrosarcoma
malignant fibrous histiocytoma
tissue microarray
Acesso em linha:https://www.mdpi.com/2072-6694/11/5/677
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