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Systematic analysis of the Hippo pathway organization and oncogenic alteration in evolution

The Hippo pathway is a central regulator of organ size and a key tumor suppressor via coordinating cell proliferation and death. Initially discovered in Drosophila, the Hippo pathway has been implicated as an evolutionarily conserved pathway in mammals; however, how this pathway was evolved to be fu...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Chen, Yuxuan, Han, Han, Seo, Gayoung, Vargas, Rebecca Elizabeth, Yang, Bing, Chuc, Kimberly, Zhao, Huabin, Wang, Wenqi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035326/
https://ncbi.nlm.nih.gov/pubmed/32081887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-60120-4
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