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Regulation of the Hippo pathway by phosphatidic acid-mediated lipid-protein interaction
The Hippo pathway plays a crucial role in organ size control and tumor suppression, but its precise regulation has not been fully understood. In this study, we discovered phosphatidic acid (PA)-related lipid signaling as a key regulator of the Hippo pathway. Supplementing PA in various Hippo-activat...
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| Veröffentlicht in: | Mol Cell |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6195446/ https://ncbi.nlm.nih.gov/pubmed/30293781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2018.08.038 |
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