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Endothelial Cell-Derived IL-18 Released During Ischemia Reperfusion Injury Selectively Expands T Peripheral Helper Cells to Promote Alloantibody Production

BACKGROUND--: Ischemia reperfusion injury (IRI) predisposes to formation of donor specific antibodies (DSA), a factor contributing to chronic rejection and late allograft loss. METHODS--: We describe a mechanism underlying the correlative association between IRI and DSA using humanized models and pa...

詳細記述

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書誌詳細
出版年:Circulation
主要な著者: Liu, Lufang, Fang, Caodi, Fu, Whitney, Jiang, Bo, Li, Guangxin, Qin, Lingfeng, Rosenbluth, Jacob, Gong, Gavin, Xie, Catherine B., Yoo, Peter, Tellides, George, Pober, Jordan S., Jane-wit, Dan
フォーマット: Artigo
言語:Inglês
出版事項: 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7035199/
https://ncbi.nlm.nih.gov/pubmed/31744330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.119.042501
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