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Endothelial Cell-Derived IL-18 Released During Ischemia Reperfusion Injury Selectively Expands T Peripheral Helper Cells to Promote Alloantibody Production
BACKGROUND--: Ischemia reperfusion injury (IRI) predisposes to formation of donor specific antibodies (DSA), a factor contributing to chronic rejection and late allograft loss. METHODS--: We describe a mechanism underlying the correlative association between IRI and DSA using humanized models and pa...
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| 出版年: | Circulation |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7035199/ https://ncbi.nlm.nih.gov/pubmed/31744330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.119.042501 |
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