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SPEN integrates transcriptional and epigenetic control of X-inactivation
Xist represents a paradigm for long non-coding RNA function in epigenetic regulation, although how it mediates X-chromosome inactivation (XCI) remains largely unexplained. Multiple Xist-RNA binding proteins have recently been identified, including SPEN(1–3), the loss of which has been associated wit...
Gorde:
| Argitaratua izan da: | Nature |
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| Egile Nagusiak: | , , , , , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7035112/ https://ncbi.nlm.nih.gov/pubmed/32025035 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-1974-9 |
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