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Segmental folding of chromosomes: A basis for structural and regulatory chromosomal neighborhoods?

We discuss here a series of testable hypotheses concerning the role of chromosome folding into topologically associating domains (TADs). Several lines of evidence suggest that segmental packaging of chromosomal neighborhoods may underlie features of chromatin that span large domains, such as heteroc...

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Detalhes bibliográficos
Main Authors: Nora, Elphège P, Dekker, Job, Heard, Edith
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874840/
https://ncbi.nlm.nih.gov/pubmed/23832846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201300040
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