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Segmental folding of chromosomes: A basis for structural and regulatory chromosomal neighborhoods?
We discuss here a series of testable hypotheses concerning the role of chromosome folding into topologically associating domains (TADs). Several lines of evidence suggest that segmental packaging of chromosomal neighborhoods may underlie features of chromatin that span large domains, such as heteroc...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Blackwell Publishing Ltd
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3874840/ https://ncbi.nlm.nih.gov/pubmed/23832846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201300040 |
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