Predictive polymer modeling reveals coupled fluctuations in chromosome conformation and transcription

A new level of chromosome organization, Topologically Associating Domains (TADs), was recently uncovered by chromosome-confirmation-capture (3C) techniques. To explore TAD structure and function, we developed a polymer model that can extract the full repertoire of chromatin conformations within TADs...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell
Egile Nagusiak: Giorgetti, Luca, Galupa, Rafael, Nora, Elphège P., Piolot, Tristan, Lam, France, Dekker, Job, Tiana, Guido, Heard, Edith
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427251/
https://ncbi.nlm.nih.gov/pubmed/24813616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.03.025
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