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Predictive polymer modeling reveals coupled fluctuations in chromosome conformation and transcription
A new level of chromosome organization, Topologically Associating Domains (TADs), was recently uncovered by chromosome-confirmation-capture (3C) techniques. To explore TAD structure and function, we developed a polymer model that can extract the full repertoire of chromatin conformations within TADs...
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| Publicat a: | Cell |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4427251/ https://ncbi.nlm.nih.gov/pubmed/24813616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.03.025 |
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