Φορτώνει......
Light-induced control of protein destruction by opto-PROTAC
By hijacking endogenous E3 ligase to degrade protein targets via the ubiquitin-proteasome system, PROTACs (PRoteolysis TArgeting Chimeras) provide a new strategy to inhibit protein targets that were regarded as undruggable before. However, the catalytic nature of PROTAC potentially leads to uncontro...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Sci Adv |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Association for the Advancement of Science
2020
|
| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7034987/ https://ncbi.nlm.nih.gov/pubmed/32128407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay5154 |
| Ετικέτες: |
Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!
|