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Structures of the M1 and M2 muscarinic acetylcholine receptor/G-protein complexes

Muscarinic acetylcholine receptors are G protein–coupled receptors that respond to acetylcholine and play important signaling roles in the nervous system. There are five muscarinic receptor subtypes (M1R to M5R), which, despite sharing a high degree of sequence identity in the transmembrane region,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Science
Hauptverfasser: Maeda, Shoji, Qu, Qianhui, Robertson, Michael J., Skiniotis, Georgios, Kobilka, Brian K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7034192/
https://ncbi.nlm.nih.gov/pubmed/31073061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaw5188
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