Insights into channel modulation mechanism of RYR1 mutants using Ca(2+) imaging and molecular dynamics

Type 1 ryanodine receptor (RYR1) is a Ca(2+) release channel in the sarcoplasmic reticulum in skeletal muscle and plays an important role in excitation–contraction coupling. Mutations in the RYR1 gene cause severe muscle diseases such as malignant hyperthermia (MH), which is a disorder of CICR via R...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Gen Physiol
Autors principals: Yamazawa, Toshiko, Ogawa, Haruo, Murayama, Takashi, Yamaguchi, Maki, Oyamada, Hideto, Suzuki, Junji, Kurebayashi, Nagomi, Kanemaru, Kazunori, Oguchi, Katsuji, Sakurai, Takashi, Iino, Masamitsu
Format: Artigo
Idioma:Inglês
Publicat: Rockefeller University Press 2019
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7034096/
https://ncbi.nlm.nih.gov/pubmed/31841587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812235
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars