Endothelial Immune Activation by Medin: Potential Role in Cerebrovascular Disease and Reversal by Monosialoganglioside‐Containing Nanoliposomes

BACKGROUND: The function of medin, one of the most common human amyloid proteins that accumulates in the vasculature with aging, remains unknown. We aim to probe medin's role in cerebrovascular disease by comparing cerebral arterial medin content between cognitively normal and vascular dementia...

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Bibliografiske detaljer
Udgivet i:J Am Heart Assoc
Main Authors: Karamanova, Nina, Truran, Seth, Serrano, Geidy E., Beach, Thomas G., Madine, Jillian, Weissig, Volkmar, Davies, Hannah A., Veldhuizen, Jaimeson, Nikkhah, Mehdi, Hansen, Michael, Zhang, Weiyang, D'Souza, Karen, Franco, Daniel A., Migrino, Raymond Q.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033828/
https://ncbi.nlm.nih.gov/pubmed/31928157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.014810
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