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Pumping the brakes on RAS – negative regulators and death effectors of RAS
Mutations that activate the RAS oncoproteins are common in cancer. However, aberrant upregulation of RAS activity often occurs in the absence of activating mutations in the RAS genes due to defects in RAS regulators. It is now clear that loss of function of Ras GTPase-activating proteins (RasGAPs) i...
Zapisane w:
| Wydane w: | J Cell Sci |
|---|---|
| Główni autorzy: | , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The Company of Biologists Ltd
2020
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7033738/ https://ncbi.nlm.nih.gov/pubmed/32041893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.238865 |
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