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Pumping the brakes on RAS – negative regulators and death effectors of RAS
Mutations that activate the RAS oncoproteins are common in cancer. However, aberrant upregulation of RAS activity often occurs in the absence of activating mutations in the RAS genes due to defects in RAS regulators. It is now clear that loss of function of Ras GTPase-activating proteins (RasGAPs) i...
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| Publicado no: | J Cell Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7033738/ https://ncbi.nlm.nih.gov/pubmed/32041893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.238865 |
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