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PRC1 Catalytic Activity Is Central to Polycomb System Function

The Polycomb repressive system is an essential chromatin-based regulator of gene expression. Despite being extensively studied, how the Polycomb system selects its target genes is poorly understood, and whether its histone-modifying activities are required for transcriptional repression remains cont...

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Detalles Bibliográficos
Publicado en:Mol Cell
Main Authors: Blackledge, Neil P., Fursova, Nadezda A., Kelley, Jessica R., Huseyin, Miles K., Feldmann, Angelika, Klose, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7033600/
https://ncbi.nlm.nih.gov/pubmed/31883950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.12.001
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