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Targeting polycomb systems to regulate gene expression: modifications to a complex story

Polycomb group proteins are transcriptional repressors that are essential for normal gene regulation during development. Recent studies suggest that polycomb repressive complexes recognise and are recruited to through a range of different mechanisms, which involve transcription factors, CpG island e...

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Détails bibliographiques
Publié dans:Nat Rev Mol Cell Biol
Auteurs principaux: Blackledge, Neil P., Rose, Nathan R., Klose, Robert J.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5469428/
https://ncbi.nlm.nih.gov/pubmed/26420232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm4067
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