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PRC1 Catalytic Activity Is Central to Polycomb System Function
The Polycomb repressive system is an essential chromatin-based regulator of gene expression. Despite being extensively studied, how the Polycomb system selects its target genes is poorly understood, and whether its histone-modifying activities are required for transcriptional repression remains cont...
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| Veröffentlicht in: | Mol Cell |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cell Press
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7033600/ https://ncbi.nlm.nih.gov/pubmed/31883950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.12.001 |
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