Enhanced digestion inhibition and mucus penetration of F127-modified self-nanoemulsions for improved oral delivery()

Self-nanoemulsifying systems (SNEs) have excellent ability to improve the solubility of poorly water-soluble drugs (PWSD). However, SNEs are likely to be degraded in gastrointestinal (GIT) when their surface is recognized by lipase/co-lipase enzyme complex, resulting in rapid release and precipitati...

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Bibliographische Detailangaben
Veröffentlicht in:Asian J Pharm Sci
Hauptverfasser: Song, Wenyi, Yang, Yuting, Yu, Miaorong, Zhu, Quanlei, Damaneh, Mohammadali Soleimani, Zhong, Haijun, Gan, Yong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Shenyang Pharmaceutical University 2018
Schlagworte:
Original Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032245/
https://ncbi.nlm.nih.gov/pubmed/32104406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2018.03.001
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