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Dual-drug nanomedicine with hydrophilic F127-modified magnetic nanocarriers assembled in amphiphilic gelatin for enhanced penetration and drug delivery in deep tumor tissue

INTRODUCTION: Deep penetration of large-sized drug nanocarriers into tumors is important to improve the efficacy of tumor therapy. METHODS: In this study, we developed a size-changeable “Trojan Horse” nanocarrier (THNC) composed of paclitaxel (PTX)-loaded Greek soldiers (GSs; ~20 nm) assembled in an...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Lai, Yen-Ho, Chiang, Chih-Sheng, Kao, Tzu-Hsun, Chen, San-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968781/
https://ncbi.nlm.nih.gov/pubmed/29861633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S161314
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