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Optimization, characterization and in vitro/vivo evaluation of azilsartan nanocrystals

Azilsartan (AZL), a poorly soluble drug, was considered to be fit for nanocrystals to improve its solubility. Our study intended to prepare AZL nanocrystals by means of bead milling method. Eight stabilizers or their binary combination and the milling time were set to be variable factors to optimize...

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Detalhes bibliográficos
Publicado no:Asian J Pharm Sci
Main Authors: Ma, Jingjing, Yang, Yinxian, Sun, Yinghua, Sun, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Shenyang Pharmaceutical University 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032236/
https://ncbi.nlm.nih.gov/pubmed/32104345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2016.09.008
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