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Optimization, characterization and in vitro/vivo evaluation of azilsartan nanocrystals

Azilsartan (AZL), a poorly soluble drug, was considered to be fit for nanocrystals to improve its solubility. Our study intended to prepare AZL nanocrystals by means of bead milling method. Eight stabilizers or their binary combination and the milling time were set to be variable factors to optimize...

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Bibliografiske detaljer
Udgivet i:Asian J Pharm Sci
Main Authors: Ma, Jingjing, Yang, Yinxian, Sun, Yinghua, Sun, Jin
Format: Artigo
Sprog:Inglês
Udgivet: Shenyang Pharmaceutical University 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032236/
https://ncbi.nlm.nih.gov/pubmed/32104345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2016.09.008
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