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Optimization, characterization and in vitro/vivo evaluation of azilsartan nanocrystals

Azilsartan (AZL), a poorly soluble drug, was considered to be fit for nanocrystals to improve its solubility. Our study intended to prepare AZL nanocrystals by means of bead milling method. Eight stabilizers or their binary combination and the milling time were set to be variable factors to optimize...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Asian J Pharm Sci
Prif Awduron: Ma, Jingjing, Yang, Yinxian, Sun, Yinghua, Sun, Jin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Shenyang Pharmaceutical University 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7032236/
https://ncbi.nlm.nih.gov/pubmed/32104345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2016.09.008
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