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In vitro and in vivo evaluation of SN-38 nanocrystals with different particle sizes
7-Ethyl-10-hydroxycamptothecin (SN-38) is a potent broad-spectrum antitumor drug derived from irinotecan hydrochloride (CPT-11). Due to its poor solubility and instability of the active lactone ring, its clinical use is significantly limited. As one of the most promising formulations for poorly wate...
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| Vydáno v: | Int J Nanomedicine |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Dove Medical Press
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5546766/ https://ncbi.nlm.nih.gov/pubmed/28814865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S133816 |
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