Amplification of Duffy binding protein-encoding gene allows Plasmodium vivax to evade host anti-DBP humoral immunity

Antigenic variation, the capacity to produce a range of variable antigens, is a well-described strategy of Plasmodium and other parasites to evade host immunity. Here, we show that gene amplification is an additional evasion mechanism used by Plasmodium vivax to escape humoral immunity targeting PvD...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Popovici, Jean, Roesch, Camille, Carias, Lenore L., Khim, Nimol, Kim, Saorin, Vantaux, Amelie, Mueller, Ivo, Chitnis, Chetan E., King, Christopher L., Witkowski, Benoit
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031336/
https://ncbi.nlm.nih.gov/pubmed/32075983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14574-9
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