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Amplification of Duffy binding protein-encoding gene allows Plasmodium vivax to evade host anti-DBP humoral immunity

Antigenic variation, the capacity to produce a range of variable antigens, is a well-described strategy of Plasmodium and other parasites to evade host immunity. Here, we show that gene amplification is an additional evasion mechanism used by Plasmodium vivax to escape humoral immunity targeting PvD...

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Dettagli Bibliografici
Pubblicato in:Nat Commun
Autori principali: Popovici, Jean, Roesch, Camille, Carias, Lenore L., Khim, Nimol, Kim, Saorin, Vantaux, Amelie, Mueller, Ivo, Chitnis, Chetan E., King, Christopher L., Witkowski, Benoit
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031336/
https://ncbi.nlm.nih.gov/pubmed/32075983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14574-9
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