Inhibition of keratinocyte necroptosis mediated by RIPK1/RIPK3/MLKL provides a protective effect against psoriatic inflammation

Psoriasis is a common autoimmune and chronic inflammatory skin disorder globally affecting 0.51–11.43% of adults. Inflammation-associated cell death in keratinocytes plays a key role in the process of integrate inflammatory cascade in psoriasis. Necroptosis is a regulated necrotic cell death mediate...

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Bibliografiska uppgifter
I publikationen:Cell Death Dis
Huvudupphovsmän: Duan, Xiaoru, Liu, Xinxin, Liu, Nian, Huang, Yuqiong, Jin, Zilin, Zhang, Song, Ming, Zhangyin, Chen, Hongxiang
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7031250/
https://ncbi.nlm.nih.gov/pubmed/32075957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2328-0
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