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Design and syntheses of peptides which induce or enhance structural changes of recombinant bovine prion protein (rbPrP) and discovery of peptides from bovine brain which accelerate structural conversions of rbPrP

The co-existence of certain peptides influenced the kinetic rate of aggregation and the lag-time of fibril formation of rbPrP. Using recently developed structural conversion assay system, peptides have been screened from bovine brain peptide library. Peptide sequences of positive components have bee...

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Publicado en:Prion
Main Authors: Nokihara, Kiyoshi, Yajima, Shunsuke, Hirata, Akiyoshi
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7030918/
https://ncbi.nlm.nih.gov/pubmed/24509486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.27961
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