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The GPI-anchoring of PrP: Implications in sorting and pathogenesis
The cellular prion protein (PrP(C)) is an N-glycosylated GPI-anchored protein usually present in lipid rafts with numerous putative functions. When it changes its conformation to a pathological isoform (then referred to as PrP(Sc)), it is an essential part of the prion, the agent causing fatal and t...
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| Veröffentlicht in: | Prion |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7030901/ https://ncbi.nlm.nih.gov/pubmed/24509692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.27892 |
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