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Structural changes of membrane-anchored native PrP(C)
Misfolding and subsequent aggregation of endogeneous proteins constitute essential steps in many human disorders, including Alzheimer and prion diseases. In most prion protein-folding studies, the posttranslational modifications, the lipid anchor in particular, were lacking. Here, we studied a fully...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2504809/ https://ncbi.nlm.nih.gov/pubmed/18669653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804721105 |
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