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Characterizing and Predicting Protein Hinges for Mechanistic Insight

The functioning of proteins requires highly specific dynamics, which depend critically on the details of how amino acids are packed. Hinge motions are the most common type of large motion, typified by the opening and closing of enzymes around their substrates. The packing and geometries of residues...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Khade, Pranav M., Kumar, Ambuj, Jernigan, Robert L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029793/
https://ncbi.nlm.nih.gov/pubmed/31786268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.11.018
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