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Computational prediction of hinge axes in proteins

BACKGROUND: A protein's function is determined by the wide range of motions exhibited by its 3D structure. However, current experimental techniques are not able to reliably provide the level of detail required for elucidating the exact mechanisms of protein motion essential for effective drug s...

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Main Authors: Shamsuddin, Rittika, Doktorova, Milka, Jaswal, Sheila, Lee-St John, Audrey, McMenimen, Kathryn
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4120148/
https://ncbi.nlm.nih.gov/pubmed/25080829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-S8-S2
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