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Characterizing and Predicting Protein Hinges for Mechanistic Insight

The functioning of proteins requires highly specific dynamics, which depend critically on the details of how amino acids are packed. Hinge motions are the most common type of large motion, typified by the opening and closing of enzymes around their substrates. The packing and geometries of residues...

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Détails bibliographiques
Publié dans:J Mol Biol
Auteurs principaux: Khade, Pranav M., Kumar, Ambuj, Jernigan, Robert L.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029793/
https://ncbi.nlm.nih.gov/pubmed/31786268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2019.11.018
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