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The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival

The Maf proteins, including c-Maf, MafA, and MafB, are critical transcription factors in myelomagenesis. Previous studies demonstrated that Maf proteins are processed by the ubiquitin–proteasome pathway, but the mechanisms remain elusive. This study applied MS to identify MafB ubiquitination-associa...

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Foilsithe in:J Biol Chem
Main Authors: He, Yuanming, Wang, Siyu, Tong, Jiefei, Jiang, Shuoyi, Yang, Ye, Zhang, Zubin, Xu, Yujia, Zeng, Yuanying, Cao, Biyin, Moran, Michael F., Mao, Xinliang
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7029123/
https://ncbi.nlm.nih.gov/pubmed/31822558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010724
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