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Combined enzymatic degradation of proteoglycans and collagen significantly alters intratissue strains in articular cartilage during cyclic compression

As degenerative joint diseases such as osteoarthritis (OA) progress, the matrix constituents, particularly collagen fibrils and proteoglycans, become damaged, therefore deteriorating the tissue’s mechanical properties. This study aims to further the understanding of the effect of degradation of the...

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Detalhes bibliográficos
Publicado no:J Mech Behav Biomed Mater
Main Authors: Pastrama, Maria-Ioana, Ortiz, Ana Caxaido, Zevenbergen, Lianne, Famaey, Nele, Gsell, Willy, Neu, Corey P., Himmelreich, Uwe, Jonkers, Ilse
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028440/
https://ncbi.nlm.nih.gov/pubmed/31349141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmbbm.2019.05.040
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