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Combined enzymatic degradation of proteoglycans and collagen significantly alters intratissue strains in articular cartilage during cyclic compression

As degenerative joint diseases such as osteoarthritis (OA) progress, the matrix constituents, particularly collagen fibrils and proteoglycans, become damaged, therefore deteriorating the tissue’s mechanical properties. This study aims to further the understanding of the effect of degradation of the...

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Podrobná bibliografie
Vydáno v:J Mech Behav Biomed Mater
Hlavní autoři: Pastrama, Maria-Ioana, Ortiz, Ana Caxaido, Zevenbergen, Lianne, Famaey, Nele, Gsell, Willy, Neu, Corey P., Himmelreich, Uwe, Jonkers, Ilse
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028440/
https://ncbi.nlm.nih.gov/pubmed/31349141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmbbm.2019.05.040
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