Combined enzymatic degradation of proteoglycans and collagen significantly alters intratissue strains in articular cartilage during cyclic compression

As degenerative joint diseases such as osteoarthritis (OA) progress, the matrix constituents, particularly collagen fibrils and proteoglycans, become damaged, therefore deteriorating the tissue’s mechanical properties. This study aims to further the understanding of the effect of degradation of the...

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Detaylı Bibliyografya
Yayımlandı:J Mech Behav Biomed Mater
Asıl Yazarlar: Pastrama, Maria-Ioana, Ortiz, Ana Caxaido, Zevenbergen, Lianne, Famaey, Nele, Gsell, Willy, Neu, Corey P., Himmelreich, Uwe, Jonkers, Ilse
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7028440/
https://ncbi.nlm.nih.gov/pubmed/31349141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmbbm.2019.05.040
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