Multivariate data analysis of growth medium trends affecting antibody glycosylation

Use of multivariate data analysis for the manufacturing of biologics has been increasing due to more widespread use of data‐generating process analytical technologies (PAT) promoted by the US FDA. To generate a large dataset on which to apply these principles, we used an in‐house model CHO DG44 cell...

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Veröffentlicht in:Biotechnol Prog
Hauptverfasser: Powers, David N., Trunfio, Nicholas, Velugula‐Yellela, Sai R., Angart, Phillip, Faustino, Anneliese, Agarabi, Cyrus
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley & Sons, Inc. 2019
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RESEARCH ARTICLES
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7027499/
https://ncbi.nlm.nih.gov/pubmed/31487120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btpr.2903
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