Multivariate data analysis of growth medium trends affecting antibody glycosylation

Use of multivariate data analysis for the manufacturing of biologics has been increasing due to more widespread use of data‐generating process analytical technologies (PAT) promoted by the US FDA. To generate a large dataset on which to apply these principles, we used an in‐house model CHO DG44 cell...

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Detalhes bibliográficos
Publicado no:Biotechnol Prog
Main Authors: Powers, David N., Trunfio, Nicholas, Velugula‐Yellela, Sai R., Angart, Phillip, Faustino, Anneliese, Agarabi, Cyrus
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
RESEARCH ARTICLES
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7027499/
https://ncbi.nlm.nih.gov/pubmed/31487120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btpr.2903
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