Impacts on product quality attributes of monoclonal antibodies produced in CHO cell bioreactor cultures during intentional mycoplasma contamination events

A mycoplasma contamination event in a biomanufacturing facility can result in costly cleanups and potential drug shortages. Mycoplasma may survive in mammalian cell cultures with only subtle changes to the culture and penetrate the standard 0.2‐µm filters used in the clarification of harvested cell...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biotechnol Bioeng
Hauptverfasser: Fratz‐Berilla, Erica J., Angart, Phillip, Graham, Ryan J., Powers, David N., Mohammad, Adil, Kohnhorst, Casey, Faison, Talia, Velugula‐Yellela, Sai Rashmika, Trunfio, Nicholas, Agarabi, Cyrus
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2020
Schlagworte:
ARTICLES
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496122/
https://ncbi.nlm.nih.gov/pubmed/32436993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.27436
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge