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Impacts of intentional mycoplasma contamination on CHO cell bioreactor cultures

Mycoplasma contamination events in biomanufacturing facilities can result in loss of production and costly cleanups. Mycoplasma may survive in mammalian cell cultures with only subtle changes to the culture and may penetrate the 0.2 µm filters often used in the primary clarification of harvested cel...

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Detalhes bibliográficos
Publicado no:Biotechnol Bioeng
Main Authors: Fratz‐Berilla, Erica J., Faison, Talia, Kohnhorst, Casey L., Velugula‐Yellela, Sai Rashmika, Powers, David N., Brorson, Kurt, Agarabi, Cyrus
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6900124/
https://ncbi.nlm.nih.gov/pubmed/31478189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.27161
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