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Asymmetric molecular architecture of the human γ-tubulin ring complex

The γ-tubulin ring complex (γ-TuRC) is an essential regulator of centrosomal and acentrosomal microtubule formation, yet its structure is not known. Here, we present a cryo-EM reconstruction of the native human γ-TuRC at ~3.8 Å resolution, revealing an asymmetric, cone-shaped structure. Pseudo-atomi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell
Egile Nagusiak: Wieczorek, Michal, Urnavicius, Linas, Ti, Shih-Chieh, Molloy, Kelly R., Chait, Brian T., Kapoor, Tarun M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7027161/
https://ncbi.nlm.nih.gov/pubmed/31862189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.12.007
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