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Asymmetric molecular architecture of the human γ-tubulin ring complex
The γ-tubulin ring complex (γ-TuRC) is an essential regulator of centrosomal and acentrosomal microtubule formation, yet its structure is not known. Here, we present a cryo-EM reconstruction of the native human γ-TuRC at ~3.8 Å resolution, revealing an asymmetric, cone-shaped structure. Pseudo-atomi...
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| Publicado en: | Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7027161/ https://ncbi.nlm.nih.gov/pubmed/31862189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.12.007 |
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