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GABA(A) Receptor β(2)E155 Residue Located at the Agonist-Binding Site Is Involved in the Receptor Gating

GABA(A) receptors (GABA(A)Rs) play a crucial role in mediating inhibition in the adult brain. In spite of progress in describing (mainly) the static structures of this receptor, the molecular mechanisms underlying its activation remain unclear. It is known that in the α(1)β(2)γ(2L) receptors, the mu...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Jatczak-Śliwa, Magdalena, Kisiel, Magdalena, Czyzewska, Marta Magdalena, Brodzki, Marek, Mozrzymas, Jerzy Władysław
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7026498/
https://ncbi.nlm.nih.gov/pubmed/32116555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00002
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