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PDCD4 controls the G1/S-phase transition in a telomerase-immortalized epithelial cell line and affects the expression level and translation of multiple mRNAs

PDCD4, the protein encoded by the tumor suppressor gene PDCD4 (programmed cell death 4) has been implicated in the control of cellular transcription and translation by modulating the activity of specific transcription factors and suppressing the translation of mRNAs with structured 5′-UTRs. Most stu...

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Publicat a:Sci Rep
Autors principals: Haas, Astrid, Nilges, Benedikt S., Leidel, Sebastian A., Klempnauer, Karl-Heinz
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7026441/
https://ncbi.nlm.nih.gov/pubmed/32066800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-59678-w
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