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Mixed messages: Re-initiation factors regulate translation of animal mRNAs
When ribosomes encounter upstream open reading frames (uORFs) during scanning of the 5′ untranslated region (5′ UTR), translation of the downstream ORF requires re-initiation. In a recent paper in Nature, Schleich et al. describe metazoan factors which specifically promote re-initiation.
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| Udgivet i: | Cell Res |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4260343/ https://ncbi.nlm.nih.gov/pubmed/25145358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2014.114 |
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